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Professor Brent R. Stockwell
Professor Brent R. Stockwell

273 Followers

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1 day ago

The critical organelle in cells that drives ferroptosis

Our new paper reports that the endoplasmic reticulum is the key site in cells that drives ferroptosis. In our new paper, we found that the endoplasmic reticulum is crucial for driving a specific type of cell death known as ferroptosis. Here is our paper, published today in Nature Chemical Biology…

Science

4 min read

The critical organelle in cells that drives ferroptosis
The critical organelle in cells that drives ferroptosis
Science

4 min read


Jan 27

Mouse motor neurons derived from embryonic stem cells undergo ferroptosis: a link to ALS?

A new study provides insight on the link between ferroptosis and ALS I want to direct you to an excellent recent publication from Professor Wan Seok Yang and his team at St. John’s University. Mouse embryonic stem-cell-derived motor neurons are susceptible to ferroptosis — PubMed Wan did his postdoctoral training…

Medicine

3 min read

Mouse motor neurons derived from embryonic stem cells undergo ferroptosis: a link to ALS?
Mouse motor neurons derived from embryonic stem cells undergo ferroptosis: a link to ALS?
Medicine

3 min read


Jan 13

Can Sulfur Save Your Brain?

Here is a conversation starter for your next party: You: “I was reading that sulfur compounds may protect against some brain diseases by inhibiting ferroptosis”. Depending on the background of your conversation partner, they might respond with one of the following: (1) Huh? (2) Sure, ferroptosis is a recently discovered…

Health

4 min read

Can Sulfur Save Your Brain?
Can Sulfur Save Your Brain?
Health

4 min read


Dec 27, 2022

Ferroptosis of Microglia Drives Neurodegeneration

A recent paper from Tim Hammond reports that microglia in the brain drive neurodegenerative diseases by undergoing ferroptosis. Neurodegenerative diseases are among the most challenging diseases for patients and drug hunters. These diseases include Parkinson’s Disease, Huntington Disease, Alzheimer’s Disease, and ALS, among others. It has been frustratingly difficult to…

Science

3 min read

Ferroptosis of Microglia Drives Neurodegeneration
Ferroptosis of Microglia Drives Neurodegeneration
Science

3 min read


Dec 23, 2022

A key to making discoveries: ask “Why?”

Asking Why? is crucial to see below the surface and find what others have missed. “There is our little Ehrlich; he is a first-rate stainer of tissues, but he will never pass his examinations,” remarked his medical school professor to future wunderkind Paul Ehrlich’s mentor, famed microbiologist Robert Koch. Another…

Creativity

6 min read

A key to making discoveries: ask “Why?”
A key to making discoveries: ask “Why?”
Creativity

6 min read


Dec 18, 2022

Adopt new technologies to drive discovery

New technologies allow researchers to collect radically different kinds of data, make striking new observations, and create further technological inventions in an exponentially growing cycle of innovation. “Every once in a while, a new technology, an old problem, and a big idea turn into an innovation.” – Dean Kamen Robert…

Technology

8 min read

Adopt new technologies to drive discovery
Adopt new technologies to drive discovery
Technology

8 min read


Dec 11, 2022

How to be visionary

Transformative discoveries require imagining the far-reaching implications of your anomalous observations. There are methods that can facilitate creating visionary ideas. “In choosing a hypothesis, there is no virtue in being timid.” – Thomas Gold In the episode “Cause and Effect” of the TV series Star Trek: The Next Generation, the…

Creativity

13 min read

How to be visionary
How to be visionary
Creativity

13 min read


Dec 5, 2022

Using classification as a tool for discovery

Classification and pattern recognition are crucial for seeing similarities among seemingly unrelated phenomena and hidden differences among seemingly identical phenomena. Classification is a powerful tool for discovery. As I described in a recent article: Making Discoveries: Find the Anomaly There is a powerful way to catalyze breakthroughs — look for anomalies that hint that something is missing in existing…brentstockwell.medium.com

Creativity

7 min read

Using classification as a tool for discovery
Using classification as a tool for discovery
Creativity

7 min read


Dec 3, 2022

New advances in how to teach and learn

Experiments with teaching and learning during the pandemic reveal new insights for how teachers should teach and how students learn best. Columbia University’s office of the Provost released a report entitled “Teaching Transformations: Faculty Reflections and Insights on Pandemic Practices”: Teaching Transformations: Faculty Reflections and Insights on Pandemic Practices This resource features reflections on pandemic teaching of Columbia faculty from across disciplines, campuses, and…ctl.columbia.edu

Teaching

3 min read

New advances in how to teach and learn
New advances in how to teach and learn
Teaching

3 min read


Nov 25, 2022

Making Discoveries: Find the Anomaly

In science class, students are often taught to follow the well-trodden path of existing hypotheses, ongoing data collection efforts, and established model systems. Advisors, thesis committee members, and fellowship grant reviewers certainly value this approach to doing science. …

Science

5 min read

Making Discoveries: Find the Anomaly
Making Discoveries: Find the Anomaly
Science

5 min read

Professor Brent R. Stockwell

Professor Brent R. Stockwell

273 Followers

Chair and Professor of Biological Sciences at Columbia University. Top Medium writer in Science, Creativity, and Ideas

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