Yes, we had a paper in Nature Chemical Biology recently about this--it is degraded through ubiquitination of two lysines

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Brent R. Stockwell, Ph.D.
Brent R. Stockwell, Ph.D.

Written by Brent R. Stockwell, Ph.D.

Chair and Professor of Biological Sciences at Columbia University. Top Medium writer in Science, Creativity, Health, and Ideas

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